| Top 100 over 2021 | a.w. | h.p | score | |
| 1 | BLIJVEN SLAPEN — Snelle x Maan | 26 | 11×1 | 1048 |
| 2 | BAD HABITS — Ed Sheeran | 24 | 6×1 | 1025 |
| 3 | STAY — The Kid Laroi & Justin Bieber | 22 | 2×1 | 1013 |
| 4 | FRIDAY — Riton x Nightcrawlers | 27 | 3 | 973 |
| 5 | THE BUSINESS — Ti?sto | 23 | 2 | 909 |
| 6 | GOOD 4 YOU — Olivia Rodrigo | 23 | 4×1 | 904 |
| 7 | WITHOUT YOU — The Kid Laroi | 22 | 3 | 878 |
| 8 | LOVE TONIGHT — Shouse | 21 | 1×1 | 878 |
| 9 | GOUD — Suzan & Freek | 21 | 2 | 825 |
| 10 | NU WIJ NIET MEER PRATEN — Jaap Reesema & Pommelien Thijs | 19 | 10×1 | 823 |
| 11 | MONTERO (CALL ME BY YOUR NAME) — Lil Nas X | 21 | 4 | 822 |
| 12 | REMEMBER — Becky Hill & David Guetta (F) | 24 | 9 | 805 |
| 13 | WELLERMAN (220Kid x Billen Ted Remix) — Nathan Evans | 20 | 2×1 | 758 |
| 14 | COLD HEART — Elton John & Dua Lipa (F) | 17 | 3×1 | 753 |
| 15 | PARADISE — Meduza & Dermot Kennedy | 20 | 5 | 731 |
| 16 | ALL WE GOT — Robin Schulz feat. Kiddo | 19 | 5 | 720 |
| 17 | DRIVERS LICENSE — Olivia Rodrigo | 18 | 2 | 712 |
| 18 | RASPUTIN — Majestic & Boney M (F) | 21 | 1×1 | 705 |
| 19 | COVER ME IN SUNSHINE — P!nk + Willow Sage Hart | 22 | 5 | 691 |
| 20 | SAVE YOUR TEARS — The Weeknd (F) | 25 | 13 | 688 |
| 21 | IKO IKO — Justin Wellington feat. Small Jam | 18 | 3 | 675 |
| 22 | HEAD & HEART — Joel Corry & Mnek | 19 | 2 | 665 |
| 23 | EARLY IN THE MORNING — Kris Kross Amsterdam ft. Shaggy | 20 | 6 | 665 |
| 24 | YOUR LOVE (9PM) — Atb x Topic x a7s | 22 | 7 | 659 |
| 25 | PEPAS — Farruko | 15 | 2 | 650 |
| 26 | HERO — Afrojack & David Guetta (F) | 23 | 11 | 646 |
| 27 | WHERE ARE YOU NOW — Lost Frequencies / Calum Scott | 16 | 6 | 630 |
| 28 | HIGHER POWER — Coldplay | 19 | 7 | 628 |
| 29 | LITTLE BIT OF LOVE — Tom Grennan | 21 | 4 | 625 |
| 30 | LOVE NOT WAR – THE TAMPA — Jason Derulo x Nuka | 17 | 7 | 620 |
| 31 | LOVE AGAIN — Dua Lipa | 17 | 6 | 600 |
| 32 | SHIVERS — Ed Sheeran | 13 | 1×1 | 596 |
| 33 | RUN — Onerepublic | 18 | 8 | 595 |
| 34 | BED — Joel Corry x David Guetta x Raye | 18 | 7 | 581 |
| 35 | VUURWERK — Camille [Be] | 29 | 21 | 577 |
| 36 | ALS IK JE WEER ZIE — Thomas Acda / Paul de Munnik / Maan / Typhoon (F) | 18 | 8 | 576 |
| 37 | TAKE MY BREATH — The Weeknd (F) | 16 | 3×1 | 575 |
| 38 | HEAT WAVES — Glass Animals | 13 | 5 | 545 |
| 39 | RISE — Lost Frequencies | 20 | 11 | 537 |
| 40 | HYPNOTIZED — Purple Disco Machine (F) | 20 | 13 | 534 |
| 41 | HEAD SHOULDERS KNEES & TOES — Ofenbach & Quarterhead (feat. Norma Jean Martine) | 17 | 5 | 533 |
| 42 | ANYONE — Justin Bieber | 15 | 7 | 528 |
| 43 | FRANS DUITS — Donnie & Frans Duijts | 23 | 11 | 528 |
| 44 | AFTERGLOW — Ed Sheeran | 17 | 9 | 525 |
| 45 | PEACHES — Justin Bieber feat. Daniel Caesar & Giveon | 15 | 5 | 520 |
| 46 | BEGGIN’ — M?neskin | 16 | 3 | 515 |
| 47 | IK GA ZWEMMEN — Mart Hoogkamer | 17 | 5 | 508 |
| 48 | BON GEPAKT — Donnie feat. Rene Froger | 14 | 6 | 506 |
| 49 | LEAVE THE DOOR OPEN — Bruno Mars, Anderson .Paak, Silk Sonic | 15 | 7 | 503 |
| 50 | YOU BROKE ME FIRST — Tate Mcrae | 14 | 4 | 497 |
| 51 | AFRAID OF THE DARK — Chef’special | 19 | 15 | 495 |
| 52 | NEVER GOING HOME – Kungs | 15 | 7 | 471 |
| 53 | ONDERWEG NAAR LATER — Suzan & Freek | 15 | 8 | 462 |
| 54 | RENDEZ-VOUS — Metejoor & Emma Heesters | 19 | 19 | 453 |
| 55 | DOOR DE WIND — Miss Montreal | 13 | 7 | 450 |
| 56 | MOOD — 24kGoldn feat. Iann Dior | 14 | 4 | 441 |
| 57 | WE ARE THE PEOPLE — Martin Garrix feat. Bono & The Edge | 16 | 2 | 439 |
| 58 | GOOSEBUMPS — Hvme | 18 | 10 | 438 |
| 59 | FEVER — Dua Lipa feat. Angele | 19 | 21 | 432 |
| 60 | KISS ME MORE — Doja Cat feat. SZA | 15 | 8 | 420 |
| 61 | MY UNIVERSE — Coldplay x BTS | 11 | 8 | 412 |
| 62 | 1 OP EEN MILJOEN – Metejoor feat. Babet | 18 | 20 | 406 |
| 63 | LOVE NWANTITI (AH AH AH) — CKay feat. Joeboy & Kuami Eugene | 13 | 7 | 404 |
| 64 | GET OUT MY HEAD — Shane Codd | 16 | 17 | 394 |
| 65 | DON’T GO YET – Camila Cabello | 14 | 14 | 391 |
| 66 | EASY ON ME — Adele | 8 | 7×1 | 389 |
| 67 | I WANNA BE YOUR SLAVE – Maneskin | 15 | 7 | 381 |
| 68 | FLOATING THROUGH SPACE — Sia x David Guetta | 18 | 19 | 376 |
| 69 | THAT’S WHAT I WANT — Lil Nas X | 11 | 11 | 376 |
| 70 | FOLLOW YOU — Imagine Dragons | 17 | 21 | 368 |
| 71 | HOLD ON — Justin Bieber | 11 | 6 | 367 |
| 72 | WHO’S LAUGHING NOW? — Ava Max | 12 | 14 | 346 |
| 73 | UHUH — $hirak feat. Ronnie Flex, Yssi SB & Lil Kleine | 13 | 14 | 341 |
| 74 | AMSTERDAM — Flemming | 8 | 2 | 338 |
| 75 | WE’RE GOOD — Dua Lipa | 14 | 19 | 333 |
| 76 | HYPERVENTILATIE — Antoon | 16 | 8 | 331 |
| 77 | ZITTI E BUONI [ESC 2021 ITALY] – Maneskin | 9 | 2 | 329 |
| 78 | PRISONER — Miley Cyrus feat. Dua Lipa | 11 | 12 | 325 |
| 79 | LONELY — Justin Bieber & Benny Blanco | 10 | 5 | 321 |
| 80 | WASTED LOVE — Ofenbach feat. Lagique | 17 | 26 | 319 |
| 81 | IN DE SCHUUR — Snelle & Ronnie Flex | 14 | 19 | 309 |
| 82 | ZOLANG JE BIJ ME BENT (F) — Jan Smit | 13 | 15 | 296 |
| 83 | LET’S LOVE — David Guetta & Sia | 10 | 10 | 294 |
| 84 | ASTRONAUT IN THE OCEAN — Masked Wolf | 11 | 12 | 287 |
| 85 | DE WERELD DRAAIT VOOR JOU — Niels Destadsbader & Regi | 18 | 27 | 286 |
| 86 | MAREA (WE’VE LOST DANCING) — Fred Again.. x The Blessed Madonna | 14 | 18 | 285 |
| 87 | HOLD ON TO ME — Just Bart (F) | 9 | 3 | 279 |
| 88 | YOU — Regard & Troye Sivan & Tate Mcrae (F) | 12 | 19 | 271 |
| 89 | SKATE — Bruno Mars, Anderson Paak, Silk Sonic (F) | 11 | 14 | 267 |
| 90 | DON’T LEAVE ME NOW — Lost Frequencies feat. Mathieu Koss (F) | 12 | 14 | 264 |
| 91 | HARD TO SAY GOODBYE — Ronde | 11 | 18 | 259 |
| 92 | DO IT TO IT — Acraze feat. Cherish | 6 | 2 | 252 |
| 93 | HURRICANE — Ofenbach & Ella Henderson (F) | 12 | 22 | 252 |
| 94 | HAWAI – REMIX — Maluma & the Weeknd | 12 | 21 | 250 |
| 95 | BLINDING LIGHTS – The Weekend | 13 | 16 | 249 |
| 96 | THUNDER — Gabry Ponte x Lum!x x Prezioso | 9 | 14 | 248 |
| 97 | LEARNING TO FLY – Sheppard (F) | 15 | 21 | 247 |
| 98 | DUIZEND STERREN — Regi & Pauline | 11 | 19 | 247 |
| 99 | SOMEONE TO YOU — Banners | 10 | 10 | 243 |
| 100 | ADEM JE IN – S10 X Frenna X Kevin | 10 | 11 | 235 |
| Paars = staat nog in de Flitsende 50 | ||||
| Groen = oude Flitsschijf | ||||
| Oranje = nummer 1 hit uit Flitsende 50 |